Usefulness of urinary antigen detection by an immunochromatographic test for diagnosis of pneumococcal pneumonia in children.
نویسندگان
چکیده
We evaluated an immunochromatographic assay detecting pneumococcal antigen in urine samples from children diagnosed with pneumococcal pneumonia. The sensitivity and specificity of the immunochromatographic test with nonconcentrated urine (NCU) were 86.7 and 62.9%, respectively; with concentrated urine (CU), they were 100 and 11.7%, respectively. Pneumococcal antigen was also detected in 42.5% of NCU and 87.1% of CU samples from nasopharyngeal carriers. This is a nonspecific test for the diagnosis of pneumococcal pneumonia in children, particularly the very young.
منابع مشابه
Diagnostic value of urinary antigen Streptococcus pneumoniae in children With pneumonia: A case control study
Abstract Background and objectives: The aim of this study was the detection of S.pneumoniae infection by rapid urinary test and blood culture in children with pneumonia in comparison with healthy children. Material and Methods: This case control study was carried out in pediatric ward of Rasoul Akram hospital in Tehran, Iran (2006 - 200٧).Fifty-four Community acquired pneumonia (CAP) and 50 hea...
متن کاملتعیین فراوانی پنومونی پنوموکوکی از طریق جدا کردن آنتی‌ژن پنوموکوک در ادرار با روش ایمونوکروماتوگرافی (Binax NOW)
Background & Aim: Streptococcal pneumoneae is the most common etiologic agent of community-acquired pneumonia. Pneumococcal isolation from sputum can only demonstrate the possibility of pnumococcal infection because of the possibility of carrying. Definitive diagnosis is made by isolation of pnumococcus from blood and sterile body fluids. Real percentage of positive blood culture in pnumococc...
متن کاملRapid diagnosis of bacteremic pneumococcal infections in adults by using the Binax NOW Streptococcus pneumoniae urinary antigen test: a prospective, controlled clinical evaluation.
The diagnosis of severe pneumococcal infections is inadequate, relying heavily on culture of Streptococcus pneumoniae from blood or other normally sterile fluids, and is severely limited by prior administration of antibiotics. We evaluated prospectively the Binax NOW S. pneumoniae urinary antigen test, a rapid immunochromatographic assay, for the diagnosis of bacteremic pneumococcal infections ...
متن کاملCurrent and potential usefulness of pneumococcal urinary antigen detection in hospitalized patients with community-acquired pneumonia to guide antimicrobial therapy.
BACKGROUND The role of pneumococcal urinary antigen detection in the treatment of adults with community-acquired pneumonia (CAP) is not well defined. We assessed the usefulness of pneumococcal urinary antigen detection in the diagnosis and antimicrobial guidance in patients hospitalized with CAP. METHODS A prospective study of all adults hospitalized with CAP was performed from February 2007 ...
متن کاملValidation of urinary antigen test for Streptococcus pneumoniae in patients with pneumococcal pneumonia.
The study was undertaken to prospectively evaluate a Streptococcus pneumoniae urinary antigen test for diagnosis of pneumococcal pneumonia among patient and control groups between 2004 and 2006. Microbiological analysis for these patients included Gram staining for sputum, sputum and blood culture. Nonconcentrated urine samples were tested using an immunochromatographic assay, the NOW S.pneumon...
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ورودعنوان ژورنال:
- Journal of clinical microbiology
دوره 41 5 شماره
صفحات -
تاریخ انتشار 2003